La galantamina postischemia es neuroprotectora
Effects of memantine and galantamine given separately or in association, on memory and hippocampal neuronal loss after transient global cerebral ischemia in gerbils.
Autores: Silvia Lorrio - Pilar Negredo - J.M. Roda - A.G.Garcia - Manuela G.Lopez
Abstract: Galantamine is an acetylcholinesterase inhibitor and memantine is a non competitive antagonist of NMDA receptors that are being used to treat Alzheimer's disease (AD) patients.The fact that drugs with different mechanisms of action are available to treat AD introduces the prospect of prescribing drug combinations to amplify drug efficacy. This study wasplaned to evaluate the potential neuroprotective effects of galantamine combined with memantine in a transient global cerebral ischemia model in gerbils. ....
Carta de respuesta de craneofaringiomas intraventriculares
Craniopharyngioma Classification. Neurosurgical Forum
Autores: J.M. Pascual - Rodrigo Carrasco - Ruth Prieto - F. Gonzalez-Llanos - Fernando Alvarez - J.M. Roda
Abstract: We read with great interest the article by Kassam et al. (Kassam AB, Gardner PA, Snyderman CH, et al: expanded endonasal approach a fully transnasal appproach for the resection of midlinesuprasellar carniopharingyomas: a new classification based on the infundibulum . J. Neurosurg 108:715-728 April 2008).
In their paper Kassam and colleagues introduced a newtopographical classification of craniopharyngiomas that isbased on the relationships of the tumor to the infundibulumand pituitary stalk, as observed in the surgical field by en-doscopic viewing...
Mejoria de transtornos de memoria experimental
Effectos of memantine and galantamine given separately or in association, on memory and hippocampal neuronal loss after transient global cerebral ischemia in gerbils.
Autores: Silvia Lorrio - Pilar Negredo - J.M. Roda - Antonio G.Garcia - Manuela G.Lopez
Abstract: Galantamine is an acetylcholinesterase inhibitor and memantine is a non competitiveantagonist of NMDA receptors that are being used to treat Alzheimer's disease (AD) patients.The fact that drugs with different mechanisms of action are available to treat AD introducesthe prospect of prescribing drug combinations to amplify drug efficacy ....