Autor: cate1

Neurosurgeons on the frontline of COVID-19: no place for surgery?

Dear Editor

We read with interest the report by Zoia, and we would like to widen the picture by sharing our experience in Madrid’s COVID-19 reference center, one of the hardest hit areas in Europe. As neurosurgeons, we never would have imagined being in the eye of the storm. We hope our humble experience can be helpful to colleagues in other countries.

Autores: Maria L. Gandía-González, Miguel Sáez-Alegre, José M. Roda

On 27 April 2020, Spain represented the hardest hitEuropean country by the COVID-19 pandemic with 219,764cases and 48.2 deaths per 100,000 inhabitants. Madrid becamethe epicenter of the outbreak, with 59,126 cases diagnosed,and a death toll of 7,922 hospitalized victims.

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Neurosurgeons on the frontline of COVID-19: no place for surgery?

Dear Editor

We read with interest the report by Zoia, and we would like to widen the picture by sharing our experience in Madrid’s COVID-19 reference center, one of the hardest hit areas in Europe. As neurosurgeons, we never would have imagined being in the eye of the storm. We hope our humble experience can be helpful to colleagues in other countries.

Autores: Maria L. Gandía-González, Miguel Sáez-Alegre, José M. Roda

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Facial nerve repair: the impact of technical variations on the final outcome

The impact of technical variations on the final outcome.

Autores: María Sánchez-Ocando - Javier Gavilán - Julio Penarrocha - Teresa González-Otero - Susana Moraleda -
José María Roda - Luis Lassaletta

Abstract: Objectives To analyze the outcome of facial nerve (FN) reconstruction, the impact of technical variations in different conditions and locations, and the importance of additional techniques in case of suboptimal results.

Patients Between 2001 and 2017, reconstruction of the FN was performed on 36 patients with varying underlying diseases. Interventions FN repair was performed by direct coaptation (n = 3) or graft interposition (n = 33). Microsurgical sutures were used in 17 patients (47%) and fibrin glue was used in all cases. Additional reinnervation techniques (hypoglossal–facial or masseter–facial transfers) were performed in five patients with poor results after initial reconstruction.

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Assesment of Overall Survival in Glioma Patients

Dear Dr Roda,

I am pleased to inform you that your manuscript ASSESSMENT OF OVERALL SURVIVAL IN GLIOMA PATIENTS AS PREDICTED BY METABOLOMIC CRITERIA has been approved for production and accepted for publication in Frontiers in Oncology, section Cancer Imaging and Image-directed Interventions.

Autores: Maria L. Gandía-González, Sebastian Cerdan, Laura Barrios, Pilar López-Larrubia, Pablo G. Feijoo, Alexis Jr. Palpan, José M. Roda, Juan Solivera

Early TLR4 blockade reduces ROS and inflammation triggered by microglial …

Dear José Roda,

Article: Early TLR4 blockade reduces ROS and inflammation triggered by microglial pro-inflammatory phenotype in rodents and human brain ischemia models

Journal: British Journal of Pharmacology

Congratulations on the acceptance of your article for publication in British Journal of Pharmacology.

Your article has been received and the production process is now underway. We look forward to working with you and publishing your article. Using Wiley Author Services, you can track your article’s progress.

Sincerely,

Wiley Author Services

Assessment of Overall Survival in Glioma Patients as Predicted by Metabolomic Criteria

We assess the efficacy of the metabolomic profile from glioma biopsies in providing estimates of postsurgical Overall Survival in glioma patients.

Autores: María L. Gandía-González - Sebastián Cerdán - Laura Barrios - Pilar López-Larrubia - Pablo G. Feijoó - Alexis Palpan Jr. - José M. Roda - Juan Solivera

Abstract: Tumor biopsies from 46 patients bearing gliomas, obtained neurosurgically in the period 1992–1998, were analyzed by high resolution 1H magnetic resonance spectroscopy (HR- 1H MRS), following retrospectively individual postsurgical Overall Survival up to 720 weeks.

The Overall Survival profile could be resolved in three groups; Short (shorter than 52 weeks, n = 19), Intermediate (between 53 and 364 weeks, n = 19) or Long (longer than 365 weeks, n = 8), respectively. Classical histopathological analysis assigned WHO grades II–IV to every biopsy but notably, some patients with low grade glioma depicted unexpectedly Short Overall Survival, while some patients with high grade glioma, presented unpredictably Long Overall Survival. To explore the reasons underlying these different responses, we analyzed HR-1H MRS spectra from acid extracts of the same biopsies

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Parada et al 2019 British Journal of Pharmacology

Inflammation takes place in both chronic and acute brain diseases and plays a key role in the development of several pathologies.

Autores: Esther Parada - Ana I. Casas - Alejandra Palomino‐Antolin - Vanessa Gómez‐Rangel - Alfonso Rubio‐Navarro - Victor Farré‐Alins - Paloma Narros‐Fernandez - Melania Guerrero‐Hue - Juan Antonio Moreno - Juliana M. Rosa - J.M. Roda - Borja J. Hernández‐García - Javier Egea

Abstract: Indeed, immune activation in the CNS is a common feature of brain injuries such as stroke, neurodegenerative diseases, and multiple sclerosis. Chronic inflammation leads to noxious effects on neurons and, thus,contributes to the pathophysiology of neurodegenerative diseases.Brain ischaemia is an acute injury that leads to the production of ROS and reactive nitrogen species (RNS), lipid peroxidation, blood–brain barrier (BBB) disruption, and exacerbated inflammation resultingin dramatic neuronal death ...

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XV Congreso SONCAM

Estimado Dr. Roda Frade

En nombre de los Comités Organizador y Científico del XV CONGRESO de la SONCAM, nuestro más sincero agradecimiento por su participación como Moderador, en la Mesa “COMPLICACIONES EN NEUROCIRUGÍA VASCULAR” que tendrá lugar el viernes, 18 de noviembre de 2016, a las 11:30 h., en el Hospital Universitario Gregorio Marañón, de Madrid.

Invite you to be one of the Chair Persons at this Annual Meeting

Dear Dr Roda

On behalf of the Board of the European Association of Neurosurgical Societies and the local organising committee in Madrid, we are delighted to invite you to be one of the Chair Persons at this Annual Meeting, which will attract around 800 international delegates. We very much hope that you will be able to join us.

As you are already aware, the EANS 2015 Annual Meeting is to be held in Madrid on October 18-21, 2015. Preparations for the Meeting are underway and we are very excited about the chosen theme, which is “Technical Advances in Neurosurgery”. We are committed to organising a high quality scientific event, which will seek both to enhance participants’ understanding of accepted best practice in neurosurgery and also to address present and upcoming challenges in the field.

On behalf of the EANS 2015 Scientific Programme Committee, we thank you in advance for your consideration and kind cooperation. It is our pleasure to invite you to the EANS 2015 Annual Meeting and hope very much you are able to join us.

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