NF2 Genetic Alterations in Sporadic Vestibular Schwannomas: Clinical Implications

NF2 gene alterations may have a clinical impact in non-NF2 vestibular schwannomas

Autores: Luis Lassaletta - Miguel Torres-Martın - Carolina Pen˜a-Granero - Jose Maria Roda - Santiago Santa-Cruz-Ruiz - Javier S. Castresana - Javier Gavilan - Juan A. Rey

Abstract:It has been suggested that NF2 mutations might correlate with clinical expression of VS in NF2 patients. The aim of this study was to analyze the impact of genetic alterationsin theNF2gene on epidemiologic, clinical, and radiologicfeatures of patients with sporadic VS. The association betweencigarette consumption and the molecular genetic findings wasalso studied.

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