Excitotoxicidad e isquemia cerebral focal experimental

Exitotoxicity and focal cerebral ischemoa induce truncation of the NR2A and NR2B subunitis of the NMDA receptor and cleavage of the scaffolding protein PSD-95

Autores: S. Gascon - M. Sobrado - J.M. Roda - A. Rodriguez-Peña - M. Diaz-Guerra

Abstract: The N-Methyl-D-aspartate type of glutamate receptor (NMDAR) plays key roles in neuronal plasticity, learning and memory in the central nervous system, fundamentally due to its high Ca2+ permeability.

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